The release of rifampicin from rifampicin gel containing polymer.
نویسندگان
چکیده
منابع مشابه
Processing and sustained in vitro release of rifampicin containing composites to enhance the treatment of osteomyelitis
The objective in this study was to develop an osteoconductive, biodegradable and rifampicin releasing bone filling composite material for the treatment of osteomyelitis, a bacterial infection of bone that is very difficult and expensive to treat. The composite material will be used together with a ciprofloxacin releasing composite, because of the rapid development of resistant bacteria when rif...
متن کاملZinc-Alginate Beads for the Controlled Release of Rifampicin
The present study describes the preparation of a carrier system based on zinc-alginate beads and to evaluate its potential for the controlled release of rifampicin, the poorly water soluble drug using ionic gelation technique. The surface topology of the developed beads were analyzed by Scanning Electron Microscopy and the crosslinking process was investigated by Fourier Transform. Infrared spe...
متن کاملCould high-concentration rifampicin kill rifampicin-resistant M. tuberculosis? Rifampicin MIC test in rifampicin-resistant isolates from patients with osteoarticular tuberculosis
PURPOSE Several studies have shown that the intralesional concentration of rifampicin in osteoarticular tuberculosis is typically at a subtherapeutic level. Sustained or controlled release by novel drug delivery systems has been investigated to maintain an effective rifampicin concentration, but the local administration of rifampicin remains controversial. Additionally, it is still unclear whet...
متن کاملChronopharmacokinetics of rifampicin.
Chronopharmacokinetics of rifampicin was studied in four healthy adult male human volunteers after drug (2.0 g) ingestion at 6.00, 12.00, 18.00 and 24.00 hr. The absorption rate constant was found to be lower and the time to reach peak concentration was longer after drug administration at 24.00 hr than at other dosing times. A second peak was observed in all individual volunteers between 6-12 h...
متن کاملPharmacokinetics of Rifampicin
founder [5]. We controlled for the significant differences between groups by adjusting for the correspondents’ variables in the multivariable analysis and treating the confounding through purposeful selection method [3]. If we consider hospitalization for pneumonia, the adjusted hazard ratio (HR) decreased when the 2 covariates history of hospitalization for pneumonia and number of outpatient v...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Hospital Pharmacy
سال: 1987
ISSN: 2185-9477,0389-9098
DOI: 10.5649/jjphcs1975.13.293